Bugün 03 Ağustos 2026 Pazartesi

TÜRKİYE PROBİYOTİK REHBERİ

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Ticari Marka Probiyotik Mikroorganizma İçeriği Ticari Form KOB (CFU) Günlük Önerilen Kullanım Miktarı Yaş/Cinsiyet Kaynağa Dayalı Destek Kullanım Alanı-Kaynağa Göre Kanıt Düzeyi
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-rhamnosus-gg-trademark-lgg
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/streptococcus-thermophilus-th-4
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/bifidobacterium-animalis-subsp-lactis-bb-12
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-paracasei-subsp-paracasei-l-casei-431
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 62- https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-acidophilus-la-5
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 63- https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/bifidobacterium-animalis-subsp-lactis-bb-12
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 62- https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-acidophilus-la-5
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Sindirim sistemini düzenleyerek bağışıklık sistemini desteklemek 1 (1)--https://www.chr-hansen.corn/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-acidophilus-la-5 --(2)--https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/bifidobacterium-animalis-subsp-lactis-bb-12 --(3)--https://www.chr-hansen.com/en/probiotic-supplements-and-infant-formula/cards/product-cards/lactobacillus-paracasei-subsp-paracasei-l-casei-431 --(4)-- https://www.chr-hansen.com/en/probiotic-supplernents-and-infant-formula/cards/product-cards/lactobacillus-rhamnosus-gg-trademark-Igg
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
İBS (İritable Bağırsak Sendromu) 1 29-Whorwell, P.J.; Altringer, L.; Moral, J.; Bond, Y.; Charbonneau, D.; O'Mahony, L.; Kiely, B.; Shanahan, F.; Quigley, E.M. (2006) Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome. American Journal of Gastroenterology, 101(7), 1581-1590.
İBS (İritable Bağırsak Sendromu) 1 30-O'Mahony, L.; McCarthy, J.; Kelly, P.; Hurley, G.; Luo, F.; Chen, K.; O'Sullivan, G.C.; Kiely, B.; Collins, J.K.; Shanahan, F.; Quigley, E.M. (2005) Lactobacillus and Bifidobacterium in Irritable Bowel Syndrome: Symptom Responses and Relationship to Cytokine Profiles. Gastroenterolgy, 128(3), 541-551.
İBS (İritable Bağırsak Sendromu) 1 31-http://www.worldgastroenterology.org/UserFiles/file/guidelines/irritable-bowel-syndrome-english-2015.pdf
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Ağız kokusu (Halitosis) 2 Güncelleniyor
Viral ve bakteriyel solunum yolu enfeksiyonu 1 Güncelleniyor
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Oral Mikrobiyota Düzenlenmesi 2 The e¡ect of ingestion of milk supplemented with salivaricin A-producingStreptococcus salivarius on the bacteriocin-like inhibitory activity of streptococcal populations on the tongue, DOI:10.1111/j.1574-6941.2006.00228.x
Oral Mikrobiyota Düzenlenmesi 3 Distribution and persistence of probiotic Streptococcus salivarius K12 in the human oral cavity as determined by real-time quantitative polymerase chain reaction, DOI: 10.1111/j.1399-302X.2007.00334.x
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
İBS (İritable Bağırsak Sendromu) 1 (1)--Ritchie, M. L.; Romanuk , T. NA. (2012) A Meta-Analysis of Probiotic Efficacy for Gastrointestinal Diseases. PLoS ONE, 7(4), 1-11. --(2)-- 2-Mc Farland L. V. (2008) A Meta-Analysis of Probiotics for the Treatment of Irritable Bowel Syndrome, World Journal of Gastroenterology, 14(17), 2650-2661.
İmmün sistemi desteklemek 1 Ritchie, M. L.; Romanuk , T. NA. (2012) A Meta-Analysis of Probiotic Efficacy for Gastrointestinal Diseases. PLoS ONE, 7(4), 1-11.
İBH (İnflamatuvar Bağırsak Hastalığı) 1 Ritchie, M. L.; Romanuk , T. NA. (2012) A Meta-Analysis of Probiotic Efficacy for Gastrointestinal Diseases. PLoS ONE, 7(4), 1-11.
Sindirim sistemini düzenlemek 1 Scientific Opinion on the substantiation of a health claim related to Saccharomyces cerevisiae var. boulardii CNCM I-3799 and reducing gastro-intestinal discomfort pursuant to Article 13(5) of Regulation (EC) No 1924/2006 EFSA Journal 2012; 10(7):2801
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
İBS (İritable Bağırsak Sendromu) 1 3- Hong, K.S.; Kang, KW.; Im, J.P.; Ji, G.E.; Kim, S.G.; Jung, H.C.; Song, I.S.; Kim, J.S. (2009) Effect of Probiotics on Symptoms in Korean Adults with Irritable Bowel Syndrome.Gut and Liver, 3(2), 101- 107.
Besin Alerjisi 2 4-Kim, J.Y.; Choi, Y.O.; Ji, G.E. (2008) Effect of Oral Probiotics(Bifidobacterium lactis AD011 and Lactobacillus acidophilus AD031) Administration on Ovalbumin- Induced Food Allergy Mouse Model. Journal of Microbiology and Biotechnology, 18(8), 1393-1400.
Atopik Dermatit 1 5- Kim, J.Y.; Kwon, J.H.; Ahn, S.H.; Lee, S.I.; Han, Y.S.; Choi, Y.O.; Lee, S.Y.; Ahn, K.M.; Ji, G.E. (2009) Effect of Probiotic Mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the Primary Prevention of Eczema: A Double-blind, Randomized, Placebo-controlled Trial. Pediatric Allergy and Immunology, 1-8.
Rotavirüsüne Bağlı Diyare 1 6-Ji, G.E.; Park, M.S.; Kin, D.;Bae, E.A. (2005) Bifidobacterium longurn AR81 (KCCM-10492) Enabling Inhibition of Rotavirus and Active Protein Separated Therefrorn.Patent Application Publication, Us 2005/0164368 A1,1-12.
Rotavirüsüne Bağlı Diyare 1 7-Park, M.S.; Kwon, B.; Ku, S.; Ji G.E. (2017) The Efficacy of Bifidobacterium longum BORI and Lactobacillus acidophilus AD031 Probiotic Treatment in Infants with Rotavirus Infection.Nutrients, 9, 1-5.
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
İnfantil Kolik 1 Güncelleniyor
Akut Diyare 1 Güncelleniyor
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Akut Diyare 1 1-Szajewska, H.; Guarino, A.; Hojsak, I.; Indrio, F.; Kolacek, S.; Shamir, R.; Vandenplas, Y.; Weizman, Z. (2014) The Use of Probiotics for The Management of Acute Gastroenteritis. A Position Paper by the ESPGHAN Working Group for Probiotics. J Pediatr Gastroenterol Nutr., 58, 531-539.
Akut Diyare 1 6-Dinleyici, EC.; Dalgic, N.; Guven, S.; Metin, O.; Yasa, O.; Kurugol, Z.; Turel, O.; Tanir, G.; Yazar, AS.; Arica, V.; Sancar, M.; Karbuz, A.; Eren, M.; Ozen, M.; Kara, A.; Vandenplas, Y. (2015) Lactobacillus reuteri DSM 17938 Shortens Acute Infectious Diarrhea in A Pediatric Outpatient Setting. J Pediatr (Rio J.), 91, 392-396.
İnfantil Kolik 1 2-Cruchet, S.; Furnes, R.; Maruy, A.; Hebel, E.; Palacios, J.; Medina, F.; Ramirez, N.; Orsi, M.; Rondon, L.; Sdepanian, V.; Xdchihua, L.; Ybarra, M.; Zablah, RA. (2015) The Use of Probiotics in Pediatric Gastroenterology: A Review of the Literature and Recommendations by Latin-American Experts. Paediatr Drugs, 17, 199-216.
İnfantil Kolik 1 3-Dryl, R.; Szajewska, H. (2018) Probiotics for Management of Infantile Colic: A Systematic Review of Randomized Controlled Trials. Arch Med Sci, 14, 1137-1143.
İnfantil Kolik 1 Anabrees, J.; Indrio, F.; Paes, B.; AlFaleh, K. (2013) Probiotics for Infantile Colic: A Systematic Review. BMC Pediatrics, 13:186.
İnfantil Kolik 1 1-Cameron, D.; Hock, QS.; Kadim, M.; Mohan, N.; Ryoo, E.; Sandhu, B.; Yamashiro, Y.; Jie, C.; Hoekstra, H.; Guarino, A. (2017) Probiotics for Gastrointestinal Disorders: Proposed Recommendations for Children of the Asia-Pacific Region. World J Gastroenterol, 23(45), 7952-7964.
Akut Diyare 1 5-Dinleyici, EC.; PROBAGE Study Group; Vandenplas, Y. (2014) Lactobacillus reuteri DSM 17938 Effectively Reduces The Duration of Acute Diarrhoea in Hospitalised Children. Acta Paediatr., 103, e300-e305.
Akut Diyare 1 2-Urbanska, M.; Gieruszczak-Bialek, D.; Szajewska, H. (2016) Systematic Review with Meta-analysis: Lactobacillus reuteri DSM 17938 for Diarrhoea! Diseases in Children. Aliment Pharmacol Ther., 43(10),1025-34.
Akut Diyare 1 3-Agustina, R.; Kok, FJ.; van de Rest, O.; Fahmida, U.; Firmansyah, A.; Lukito, W.; Feskens, EJM.; van den Heuvel, EGHM.; Albers, R.; Bovee-Oudenhoven, IMJ. (2012). Randomized Trial of Probiotics and Calcium on Diarrhea and Respiratory Tract Infections in Indonesian Children. Pediatrics, 129, e1155-e1164.
Akut Diyare 1 4-Gutierrez-Castrellon, P.; Lopez-Velazquez, G.; Diaz-Garcia, L; Jimenez-Gutierrez, C.; Mancilla-Ramirez, J.; Estevez-Jimenez, J.; Parra, M. (2014) Diarrhea in Preschool Children and Lactobacillus reuteri: A Randomized Controlled Trial. Pediatrics, 133, e904-e909.
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Akut Diyare 1 Güncelleniyor
İnfantil Kolik 1 Güncelleniyor
Kaynağa Dayalı Destek Kullanım Alanları
Destek Alanı Seviye Kaynak
Vajinal Mikrobiyom Modülasyonu https://www.ncbi.nlm.nih.gov/biosample/57113622